These Charts have been provided by:

Amiral J Vissac AM.
HYPHEN BioMed

• Measuring the APC Resistance associated with Factor V-L, quantitatively

• N/A

HEMOCLOT Schemes

Protein C/Protein S and AT III Pathways

• Regulation of Blood Coagulation Through the Protein C Pathway

Factor V-Leiden

• Quantitative Assay for Measuring Factor V-Leiden Concentration in Plasma by it’s Resistance to the Action of Activated Protein C
• New Quantitative Assay for V-Leiden
• Quantitative Measurement of Factor V-Leiden with a New, One Step, Calibrated, Clotting Assay
• Classification of Factor V-Leiden Carriers by Quantitatively Measuring it’s Procoagulant Activity Comparatively to that of Factor V
• Quantitative Measurement of Factor V- Leiden Heterozygous and Homozygous Patients for the R506Q Factor V Mutation
• Evaluation of a Novel Quantitative Assay for Factor V Leiden
• Acceptance Range of Clotting Time for Act PC-r When Using HEMOCLOT FV-L Device (Ref. ACK061K/L) with Water Bath or STA-R

Webpage

• Check out our Hyphen BioMed Web Page

Kits: HEMOCLOT Quanti V-L (Ref. ACK065K)

Videos

HEMOCLOT Quanti. V-L (ACK065K) kit is a clotting method proposed for measuring Factor V-L (Factor V Leiden) concentration in citrated plasma, by its resistance to the action of Activated Protein C (APC). The assay is performed in the presence of Activated Protein C. In presence of APC and Protein S (in excess), the prolongation of clotting time is directly related to the concentration of Normal Factor V, and inversely related to the amount of Factor V-Leiden (mutation R506Q).

Assay Characteristics

• Quantitative reagent for measuring Factor V-L.
• No interference of plasma factor deficiencies (Other than that of Factor V).
• Excellent discrimination between Heterozygous, Homozygous and Normals.
• Single test method performed with only one Clotting Time (CT).
• 510(k) Cleared for In Vitro Medical Diagnostic Use.

SKU # ACK065K HEMOCLOT
Quanti-V-L

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Calibrators: Factor V-L Calibrator (Ref A222401)

Assay Characteristics

• Lyophilized, prediluted human plasmas, at defined Factor V-Leiden (FV-L) concentrations, for the calibration of Factor V-L activity quantitative clotting assay on human citrated plasma, using the HEMOCLOT Quanti. V-L kit (ref ACK065K).
• 510(k) Cleared for In Vitro Medical Diagnostic Use.

Controls: BIOPHEN Normal Control Plasma (Ref. A223201)

Assay Characteristics

• Normal plasma for the quality control of assays for Protein C, Antithrombin, Factor VIII:C and Factors VII+X. The exact concentration and the acceptance ranges for each factor are indicated on the flyer provided with each kit.
• 510(k) Cleared for In Vitro Medical Diagnostic Use.

Controls: BIOPHEN Act PC-r Control Plasma (Ref. A223405)

Assay Characteristics

• Plasma presenting an Activated Protein C Resistance (heterozygous).
• 510(k) Cleared for In Vitro Medical Diagnostic Use.